热应激和胎盘缩:一个时空分层的案例交叉研究
Shuhei Terada1, Hisaaki Nishimura1, Naoyuki Miyasaka2
1Department of Public Health, Institute of Science Tokyo, Tokyo, Japan.
概括
用湿球球体温度 (WBGT) 测量的热应激与在7天内发生胎盘断裂的风险更高有关. 这种风险特别高于怀孕期间有高血压疾病的孕妇或怀孕期婴儿较小的孕妇.
科学领域:
- 环境健康 环境健康
- 产科 产科 产科 产科 产科
- 围产期流行病学 围产期流行病学
背景情况:
- 热应激是一个日益关注的问题,特别是在怀孕期间.
- 胎盘断裂是一种严重的产科并发症,具有重大的孕产妇和胎儿风险.
- 了解胎盘断裂的环境触发因素对于公共卫生至关重要.
研究的目的:
- 调查热应激和胎盘断裂之间的关联.
- 为了确定暴露于热量和胎盘断裂开始之间的时间关系.
主要方法:
- 采用了一个时空分层的案例交叉设计.
- 数据包括来自日本 (2011-2020) 的6947例胎盘断裂病例.
- 用分布式滞后模型进行准松回归,评估热应力 (WBGT) 和0-7天内胎盘断裂风险.
主要成果:
- 热应激显示,延迟1时胎盘断裂的风险增加 (RR:1.23).
- 在妊娠高血压障碍 (HDP) 和妊娠年龄小 (SGA) 婴儿的怀孕中观察到更高的风险.
- 在0-7天的累积风险被延迟2的较低风险所抵消.
结论:
- 热应激可能会在暴露后24小时内导致胎盘断裂.
- 这些发现表明,热应激可能会推进胎盘断裂的时间.
- 有HDP或SGA婴儿的孕妇似乎更容易受到热应激诱导的胎盘断裂的影响.
关键词:
胎盘突然发生 胎盘突然发生环境温度 环境温度 环境温度气候变化 气候变化 气候变化流行病学流行病学全球变暖全球变暖热量警报 热量警报 热量警报湿度 湿度 湿度 湿度延迟效应是一种延迟效应.湿灯泡地球温度 地球温度更多相关视频
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