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怀孕期间和产后第一年的甲状腺功能下降和甲状腺功能下降症妇女之间的失禁特征的比较:一项前性观察性研究
Kaiyue Wang1, Linjuan Ji1, Jun Huang1
1Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
孕期甲状腺功能低下会增加尿失禁 (UI) 的严重程度,并在怀孕和产后期间对生活质量 (QoL) 产生负面影响. 这种效应在产后3-4个月后变得不那么明显.
科学领域:
- 产科和妇科 产科和妇科
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
背景情况:
- 孕期甲状腺功能低下症是一种影响孕妇的疾病.
- 尿失禁 (UI) 和其对生活质量 (QoL) 的影响是怀孕和产后的重大问题.
- 妊娠性甲状腺功能低下症和UI之间的关系需要进一步调查.
研究的目的:
- 评估怀孕期和产后尿失禁 (UI) 的发生和严重程度在怀孕期甲状腺功能低下症的孕妇中.
- 评估UI对该人口生活质量 (QoL) 的负面影响.
- 为了比较妊娠性甲状腺功能低下症和没有妊娠性甲状腺功能低下症的女性之间的UI参数.
主要方法:
- 一项涉及522名符合条件的妊娠性UI患者的研究,分为甲状腺功能低下UI (HUI) 和甲状腺功能良好UI (EUI) 组.
- 数据收集包括人口参数,临床特征和UI配置文件,使用国际商失禁问卷-尿失禁简单表格 (ICIQ-UI-SF).
- 在怀孕期间进行了评估,分娩后6-7周,分娩后3-4个月和分娩后一年,包括1小时的板测试以测试泄漏严重程度.
主要成果:
- 妊娠性UI的总体患病率为45.4%.
- 与EUI组相比,HUI组在怀孕期间和产后 (长达一年) 显示出明显更高的泄漏频率,数量和对QOL的负面影响.
- 在产后3至4个月的随访中,没有观察到UI参数的显著跨组差异.
结论:
- 妊娠性甲状腺功能低下症与UI频率,数量和严重程度的增加有关.
- 妊娠性甲状腺功能低下症加剧了UI在怀孕期间和产后第一年对失禁特异性QoL的负面影响.
- 孕期甲状腺功能低下症和孕期和产后UI之间存在潜在的关系.
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