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Updated: May 8, 2025

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
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接受万科米辛的新生儿中毒性风险因素:系统性审查和元分析

Yuan Gao1,2, Tong Wu2, Libin Pu2

  • 1Department of Pharmacy, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.

Paediatric drugs
|April 10, 2025
PubMed
概括

在新生儿中鉴定香草素诱导的毒性风险因素至关重要. 富罗塞米德,安福特里辛B,专利性动脉通道,死性肠球炎和高米辛水平会增加风险,而氨基甘油则不会.

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When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
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