母亲的饮食模式,母乳养时间,以及它们与孩子的认知功能和头周长增长的关联:一项前性母婴队列研究
David Horner1, Jens Richardt Møllegaard Jepsen2,3, Bo Chawes1
1COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Gentofte, Denmark.
PLoS medicine
|April 10, 2025
概括
怀孕期间母亲的饮食会影响孩子的神经发育. 多样化的饮食与更高的智商有关,而西方饮食与较低的认知分数和减少头部生长有关.
科学领域:
- 神经发育科学 神经发育科学
- 营养科学 营养科学
- 儿科卫生健康 儿科卫生健康
背景情况:
- 早期生命对神经发育至关重要,母亲的营养和母乳养会影响头周和认知结果.
- 母亲的饮食模式和母乳养时间是儿童发育的关键因素.
研究的目的:
- 调查怀孕期间母亲饮食模式,母乳养时间,儿童头周和认知发育之间的关联.
- 探索母亲饮食对神经发育轨迹的影响.
主要方法:
- 利用了哥本哈根前性儿童喘研究2010年队列 (700对母婴对) 的数据.
- 使用食物频率问卷和代谢组数据评估怀孕期间的饮食模式 ("多样化"",西方").
- 测量了从怀孕20周到10周的头周长以及使用贝利尺度和韦克斯勒智力尺度的认知发育.
- 使用多基因风险评分对遗传影响进行控制.
主要成果:
- 怀孕期间的西方饮食模式与2.5岁时的认知分数降低和头周长增长减少有关.
- 一种多样化的饮食模式与10岁时更高的估计智商有关,头周长的增长调解了这一效应.
- 延长母乳养时间独立与头周长增长相关.
结论:
- 怀孕和母乳养期间的母亲营养对于最佳的神经发育结果至关重要.
- 公共卫生战略应促进健康的孕产妇饮食习惯,以支持儿童的认知和身体发展.
- 头周长的增长在调解多样化的孕产妇饮食对认知发育的积极影响方面发挥着作用.
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