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在早产后小鼠中,微质LXRβ的无活化会损害微质的稳定性,并导致长期的认知功能障碍

Keyi Lv1, Yi Luo1, Tianyao Liu1

  • 1Department of Military Cognitive Psychology, School of Psychology, Third Military Medical University (Army Medical University), Chongqing 400038, China.

Proceedings of the National Academy of Sciences of the United States of America
|April 10, 2025
PubMed
概括

从发育中的微质中去除肝X受体β (LXRβ) 会损害大脑免疫细胞的功能,并导致认知缺陷. 成年人去除显示没有认知影响,突出早期LXRβ的重要性.

关键词:
在LXRββ.认知功能 认知功能微质细胞中的微质细胞微质细胞的恒常性.突触的吞没 突触的吞没

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