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Updated: May 15, 2025

Detection of a CDH1 Rare Transcript Variant in Fresh-frozen Gastric Cancer Tissues by Chip-based Digital PCR
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用数字PCR方法识别血液恶性瘤中的TP53复制数变异.

Wei Zhao, Dongming Yao, Qian Yuan

    Clinical laboratory
    |April 10, 2025
    PubMed
    概括

    数字PCR准确量化了血液恶性瘤中TP53拷贝数变异 (CNV) 的数量. 该方法提供了一种可靠且具有成本效益的解决方案,用于在临床环境中检测TP53 CNV状态.

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    相关概念视频

    Comparing Copy Number Variations and SNPs02:26

    Comparing Copy Number Variations and SNPs

    Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
    Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
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