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Updated: May 15, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

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通过调节Th17细胞分化,素乳增强的IRF4与酸盐诱导的肝纤维化有关

Weiyong Chen1, Peiwen Wang2, Yan Xie3

  • 1Center for Global Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute for Advanced Study of Public Health, Gusu School, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China; Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.

Chemico-biological interactions
|April 10, 2025
PubMed
概括

暴露会增加乳酸盐,从而导致肝纤维化,而乳酸盐通过组织素乳化促进Th17细胞分化. 抑制乳酸生产可以缓解肝纤维化,提供新的治疗策略.

关键词:
亚石是一种亚石.肝星细胞的激活方式希斯的乳酸化 希斯的乳酸化肝脏纤维化 肝脏纤维化Th17细胞分化的过程

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