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Updated: May 15, 2025

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality
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热挤出,喷雾干燥和KinetiSol®加工的比较研究,以制备一种水溶性较差和热可溶性药物

Miguel O Jara1, Beatriz Behrend-Keim1, Giselle Bedogni2

  • 1Molecular Pharmaceutics and Drug Delivery Division, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA.

International journal of pharmaceutics
|April 10, 2025
PubMed
概括

粉末释放的KinetiSol加工 (pKSD) 成功提高了难溶性药物芬班达 (FBZ) 的溶性. 这种新的方法避免了热降解,为热可融化合物提供了比热挤出和喷雾干燥更优质的替代方案.

关键词:
无形固体分散的分散.化学降解 化学降解本达 (Fenbendazole) 是一种一种热挤出方法 热挤出这就是KinetiSol.微晶体是一种微晶体.喷雾干燥 喷雾干燥

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