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Updated: May 15, 2025

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神经关联基因FOXD1通过调节黑色素瘤中的骨髓系衍生抑制细胞来诱导免疫抑制的微环境

Qian Sun1,2, Nina Wang1,2, Juliane Poelchen1,2

  • 1Skin Cancer Unit, German Cancer Research Center (DKFZ) and DKFZ Hector Cancer Institute, Heidelberg, Baden-Württemberg, Germany.

Journal for immunotherapy of cancer
|April 10, 2025
PubMed
概括

叉头盒 D1 (FOXD1) 通过通过介素-6 (IL6) 增加免疫抑制性髓质衍生抑制细胞 (MDSC) 来促进黑色素瘤的进展. 向FOXD1或IL6可能会提高免疫治疗对黑色素瘤的有效性.

关键词:
免疫抑制是一种免疫抑制.骨髓系衍生抑制细胞 - - MDSC皮肤癌 皮肤癌 皮肤癌瘤微环境 - - 瘤微环境

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