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一种非传统的自途径,在细胞亡过程中抑制ATP分泌

Elena Terraza-Silvestre1, Raquel Villamuera1, Julia Bandera-Linero1

  • 1Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Nicolás Cabrera, 1, 28049, Madrid, Spain.

Nature communications
|April 10, 2025
PubMed
概括

一种新型的自途径阻止了从垂死的细胞中释放腺三酸盐 (ATP),一种与损伤相关的分子模式 (DAMP). 这种机制确保了细胞亡的细胞死亡保持免疫沉默,防止不必要的免疫反应.

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