最好的人类指数可以预测结肠癌
Kaihao Wang1, Anlei Wang1, Shaozu Wang1
1Department of General Surgery, Xingtai People's Hospital, No.16 Hongxing Street, Xiangdu District, Xingtai, 054000, Hebei, China.
BMC gastroenterology
|April 11, 2025
概括
身体形状指数 (ABSI),圆度指数 (ConI) 和体重调整的腰部指数 (WWI) 是结肠癌最有效的人类测量预测指标. 这些简单的测量可以帮助早期检测,特别是在资源有限的地方.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 生物统计学 生物统计学
背景情况:
- 结肠癌是全球主要的恶性瘤.
- 存在众多的人类测量指标,但结肠癌最可靠的预测指标仍然未确定.
- 这项研究解决了为结肠癌预测确定有效的人类指标的需要.
研究的目的:
- 为了确定预测结肠癌的最有效的人类指标.
- 评估结肠癌各种人类指数的预测准确度.
- 突出腹部肥胖在结肠癌预测中的临床相关性.
主要方法:
- 从国家健康和营养检查调查 (NHANES) 的数据分析,涵盖2005-2018年.
- 结肠癌患者和对照组之间的人类测量结果的比较.
- 统计分析包括曲线下的面积 (AUC) 计算,以评估预测准确性.
主要成果:
- 在病例和对照人群之间观察到年龄,种族,吸烟,糖尿病,高血压,腰围,身体形状指数 (ABSI),身体圆度指数 (BRI),度指数 (ConI),腰与身高比率 (WHtR) 和体重调整后腰指数 (WWI) 的显著差异 (P <0.05).
- ABSI (AUC:0.68),ConI (AUC:0.68) 和第一次世界大战 (AUC:0.67) 成为预测结肠癌的最准确的人类指数.
- ABSI,ConI和第一次世界大战显示出强烈的相关性,表明它们的综合效用.
结论:
- ABSI,ConI和WWI被确定为结肠癌的最佳人类预测指标,AUC范围为0.67-0.68.
- 这些发现强调了腹部肥胖在结肠癌背景下的临床重要性.
- 这些指数的成本效益表明它们有潜力提高早期结肠癌查,特别是在资源有限的环境中.
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