发展身体活动和久坐行为值,用于心脏病的二次预防 (DASSH):一个队列死亡率生存树分析分析
Nicole Freene1, Amanda Lönn2,3, Theo Niyonsenga2
1Health Research Institute, University of Canberra, Bruce, ACT, 2617, Australia. Nicole.Freene@canberra.edu.au.
概括
确定了冠心病 (CHD) 死亡率的身体活动和久坐行为值. 目前的公共卫生指南适用于所有原因的死亡率,但较低的体力活动值可能有利于心脏死亡风险.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 体力活动,久坐不动行为 (SB) 和冠心病 (CHD) 患者死亡率之间的关系需要澄清.
- 确定适度至强度体力活动 (MVPA) 和SB的具体门对于风险评估至关重要.
研究的目的:
- 确定与心脏病患者所有原因和心脏病死亡率相关的MVPA和SB的剂量反应值.
- 将这些确定的值与现有的公共卫生指南进行比较.
主要方法:
- 这是一项从2006年到2020年对40156名澳大利亚成年人 (≥45岁) 进行的前性队列研究,他们自行报告了心血管疾病.
- 使用生存回归树和考克斯回归模型来确定死亡率结局的MVPA (min/wk) 和SB (hr/day) 值.
- 分析检查了性别特异性差异,并将确定的门与公共卫生指南进行了比较.
主要成果:
- 在11.1年的随访期间,发生了2497例心脏病死亡和12240例全因死亡.
- 死亡率值被确定为≥146分钟/周MVPA所有原因死亡率和≥96分钟/周心脏死亡率.
- 对于降低死亡风险,静坐行为值为每天<5-6小时. 观察到特定于性别的差异.
结论:
- 公共卫生体育活动指南似乎适用于降低心脏病患者全因死亡风险.
- 较低的MVPA值可能有助于降低心脏病死亡风险.
- 降低死亡风险的推SB值为每天5-6小时,需要进一步调查性别特异性的变化.
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