支气管切除术在患有支气管肺形的儿童中的结果
Ada Cleary Sher1,2, Humra Shamim1, Jemma Maynard3
1Center for Regenerative Medicine, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio, USA.
支气管切除术在患有支气管肺形症 (BPD) 的儿童中死亡率较低,但大多数经历了不良事件和再录取. 对于空气道干预措施,需要进一步的研究.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 儿科肺病学 儿科肺病学
- 新生儿科学 新生儿科学
背景情况:
- 支气管肺张力症 (BPD) 是婴儿的慢性肺部疾病,通常需要呼吸道支持.
- 气管切除术是BPD的气管切除术依赖的儿童的常见干预措施.
- 在这个脆弱人群中量化气管切除术相关的结果对于临床管理至关重要.
研究的目的:
- 为了确定患BPD需要气管切除的儿童的发病率,死亡率,再接收率和呼吸道干预需求.
- 分析气管切除术相关并发症的类型和频率.
- 确定影响该患者群体结果的因素.
主要方法:
- 对76名患有BPD的婴儿进行了回顾性图表审查,这些婴儿接受了气管切除术.
- 收集的数据包括患者特征,临床接触和手术访问.
- 对幸存的患者进行至少2岁的随访.
主要成果:
- 总体死亡率为30.3%,其中有一个与气管切除术相关的死亡.
- 气管炎是最常见的不良事件 (21%短期,81%长期).
- 观察到高比例的胃颗粒瘤 (77%),气道狭窄 (69%) 和意外脱毛 (38%). 报道了32%的30天和61%的2年再入院率,主要是气管炎. 68%的幸存者在平均年龄为3.1岁时被脱,其中85%需要呼吸道手术干预,其中43%需要重建.
结论:
- 尽管经常出现不良事件和再入院,但在这个BPD队列中,气管切除术相关的发病率很低.
- 伴随性疾病,BPD严重程度和社会经济地位并没有显著影响结果.
- 建议进行更大规模的研究,以进一步评估 BPD 的儿科气管切除术患者的呼吸道干预和结果.
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