术前的身体组成指标作为结直肠癌手术结果的预测指标
Dorsa Salabat1, Asma Mousavi1,2, Shayan Shojaei1,2
1School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Annals of medicine and surgery (2012)
|April 11, 2025
概括
在结直肠癌患者中,内脏脂肪和肉的增加预示着手术结果更差. 身体组成指标可以指导术前评估,但需要进一步的研究才能得到一致的应用.
科学领域:
- 在瘤学瘤学.
- 外科手术的结果
- 身体组成分析 身体成分分析
背景情况:
- 结肠直肠癌 (CRC) 手术风险包括,阻塞和感染.
- 手术前的身体组成 (BC) 测量越来越多地研究它们对CRC手术结果的影响.
- 关于BC指标和并发症的现有数据分散和不一致.
研究的目的:
- 系统地评估所有报告的手术前身体组成测量结果在结直肠癌手术中的预测值.
- 综合分散和不一致的关于CRC患者身体组成和手术并发症的数据.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在主要数据库 (PubMed,Scopus,Web of Science,Embase) 进行全面的文献搜索,直到2024年1月.
- 包括原始研究报告手术前BC参数和CRC患者的术后结果,与数据提取和概率比率和置信区间的元分析.
主要成果:
- 对19项涉及7416名患者的研究进行了分析.
- 更高的内脏脂肪区域与术后并发症增加有关 (MD = 31.91).
- 麻症与较高的整体术后并发症 (RR = 1.24) 发生率,大肠 (RR = 1.40) 和再入院 (RR = 2.18) 发生率有关,但不涉及感染,泄漏,阻塞或LOS.
结论:
- 手术前的身体组成指标显示,它们有可能成为特定结直肠癌手术结果和并发症的预测指标.
- 需要进一步的研究,采用更加均的方法.
- 标准化BC评估可能会被整合到常规CRC患者的手术前评估中.
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