对一种新型纤维产品的开放标签研究,用于膨胀,气体和肠道规律性
Alexander S Ganz1, Brooke Greeley2, James Riggen3
1Department of Biology, Southern Methodist University, Dallas, NC, United States.
Frontiers in medicine
|April 11, 2025
概括
这项研究发现,纤维补充剂Relievance显著改善了慢性胃肠道问题患者的肠道规律,并减少了胀气和气体症状. 该补充剂在六周的时间内显示出良好的安全性.
科学领域:
- 胃肠病学 胃肠病学
- 饮食纤维研究 饮食纤维研究
- 临床营养学 临床营养学
背景情况:
- 慢性胃肠道症状,如胀气,气体和不规则的肠道排便,影响了许多人.
- 食纤维对消化系统的健康和规律性起着至关重要的作用.
- 新型纤维混合物正在开发中,以解决这些常见的消化不良问题.
研究的目的:
- 评估一种新的纤维补充剂Relievance在改善肠道运动规律性的有效性.
- 评估Relievance对减轻膨胀和气体症状的影响.
- 确定Relievance在患有慢性胃肠道症状的患者群体中的安全性.
主要方法:
- 一项开放性研究涉及20名连续患有慢性胃肠道症状的患者.
- 参与者每天摄入大约6克的Relievance (8种天然纤维的混合物),每天服用一至三次,持续6周.
- 肠道排便频率和症状严重程度 (胀气,气体) 用日记和6点模拟尺度记录.
主要成果:
- 平均每周排便量显著增加,从基线时的1.7增加到研究结束时的3.2.
- 膨胀和气体的症状严重性得分从基线时的3.0显著下降到6周后的1.5.
- 没有报告任何重大不良事件,这表明安全性概况良好.
结论:
- 纤维混合物Relievance似乎有效地提高了肠道排便的频率,并缓解了胀气和气体症状.
- 这项研究表明,Relievance对于患有慢性消化不适的人来说是一个安全的选择.
- 建议进行进一步的随机对照试验,以证实这些初步发现.
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