改善脏移植接受者生活参与的干预措施:系统性审查
Patrizia Natale1,2, Angela Ju1, Martin Howell1,3,4
1Sydney School of Public Health, The University of Sydney, Sydney, Australia.
Kidney medicine
|April 11, 2025
概括
这次系统性审查没有发现任何专门测量移植接受者的生命参与度的研究. 需要更多的研究来了解改善这些患者日常生活活动的干预措施.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植医学 移植医学
- 康复科学 康复科学 康复科学
背景情况:
- 参与生活,对移植接受者的生活质量至关重要,涉及参与有意义的日常活动.
- 评估加强生活参与的干预措施对于移植后的护理至关重要.
- 目前对影响生活参与的干预措施的证据有限.
研究的目的:
- 系统地审查随机对照试验,评估移植患者参与生活的干预措施.
- 评估各种干预措施对改善移植后有意义的日常活动的有效性.
主要方法:
- 进行了随机对照研究的系统审查.
- 在MEDLINE,Embase,CENTRAL,PsycINFO和CINAHL进行了搜索,截至2023年3月.
- 数据提取和偏差风险评估由两位作者独立进行.
主要成果:
- 在14162份报告中,包括了33项研究,共有4857名参与者.
- 没有研究特别指出"生活参与"作为结果.
- 在15%,15%和33%的研究中,分别报告了精神,身体和社会功能,在大多数领域中偏差风险很高或不清楚.
结论:
- 对诸如益生菌,ESA,免疫抑制剂,运动,营养,教育和手术等干预措施对生活参与相关结果的证据仍然不确定.
- 显著缺乏专门测量移植接受者的生命参与度的研究.
- 迫切需要进一步进行高质量的试验,以确定有效的干预措施,以改善移植接受者的生活参与.
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