约旦的人类乳头瘤病毒-对650例病例的选择性研究
Abeer W Annab1,2,3, Isam M Lataifeh4,5,6, Yahia F Dajani7,8,9
1Al-Amal Hospital Medical Complex, Ministry of Interior Circle, Jabal Al-Hussein, Amman, Jordan.
IJID regions
|April 11, 2025
概括
人类乳头瘤病毒 (HPV) 感染在约旦阿曼普遍存在,经常检测到高风险的HPV基因型. 这些发现支持HPV疫苗接种计划,以减少宫癌的发生率.
科学领域:
- 妇科 妇科 妇科 妇科
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 宫癌是全球和约旦的重大健康问题.
- 了解人类乳头瘤病毒 (HPV) 的流行率和类型对于预防策略至关重要.
研究的目的:
- 在约旦阿曼社区调查HPV感染的发生情况.
- 分析HPV基因型,年龄分布和与子宫瘤相关的结果.
主要方法:
- 在2011-2023年期间,总共从阿曼的妇科诊所收集了650个样本.
- 使用基于液体的细胞学和使用逆转录-聚合酶链反应的HPV基因型鉴定.
- 阳性病例被分为高风险 (HR-HPV) 和低风险 (LR-HPV) 基因型,并分析单一,多重或混合感染.
主要成果:
- 在25.7%的约旦本地人和23.2%的外籍人士中检测到HPV感染.
- 高风险的HPV基因型,特别是HPV 16,是最常见的 (本地人中75%,外籍人士中79%).
- 异常的宫涂抹和瘤与HR-HPV有关;36%的感染在平均后续2.8年内清除.
结论:
- 宫性HPV,特别是HR-HPV,是约旦安曼的一个值得注意的问题.
- 流行数据和已识别的HR-HPV基因型强调了需要HPV疫苗接种计划的必要性.
- 建议进行进一步的研究,以将发病率分析扩展到约旦其他地区.
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