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不确定的冠状腺黑色细胞瘤的生长:到恶性转变的时间

Zackery Oakey^1,2, Yağmur Seda Yeşiltaş^1,3, Emily C Zabor⁴

¹Cleveland Clinic, Cole Eye Institute, Cleveland, OH, USA.

Taiwan journal of ophthalmology

|April 11, 2025

概括

两年内不确定的冠状腺黑色细胞瘤 (IMTs) 的早期生长可能表明黑色素瘤. 稳定后的晚期生长表明胆道神经的恶性转变.

科学领域:

眼科医生眼科眼科
在瘤学瘤学.
医疗成像医学成像

背景情况:

不确定的冠状腺黑色细胞瘤 (IMTs) 存在诊断方面的挑战.
早期与晚期瘤生长的临床意义尚不清楚.
区分良性瘤和恶性黑色素瘤对于患者的治疗结果至关重要.

研究的目的:

分析IMT增长的时间概况.
为了确定早期和晚期瘤生长模式之间的潜在差异.
为了将生长模式与恶性瘤 (冠状腺黑色素瘤) 的可能性相关联.

主要方法:

对9项已发表的研究 (1977-2021) 进行系统审查,其中包括8766名患者.
对瘤生长的时间到事件数据的分析.
包括观察到生长的不确定的或可疑的胸腔瘤.

主要成果:

在8606个瘤中,5.6%的瘤在5年内增长.
增长率最高的发生在第一年 (平均6.5%).
大多数瘤 (平均67%) 在前两年内表现出早期生长;晚期生长不太常见.

结论:

IMT的早期生长 (2年内) 可能意味着正在发展的冠状腺黑色素瘤.
经过一段时间的稳定之后,晚期生长可能表明胆道神经的恶性转变.
时间生长模式是区分IMT良性和恶性子集的关键.

关键词:

冠状腺黑色素瘤 (choroidal melanoma) 是一种黑色素瘤.冠状腺神经冠状腺神经不确定的黑色细胞病变.不确定的黑色素细胞瘤小型冠状腺黑色素瘤

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