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代谢性减肥手术后怀孕的孕产妇和新生儿结果:一项以人口为基础的回顾性研究
Pierre Bel Lassen1,2,3, Anne-Isabelle Tropeano4,5, Armelle Arnoux4,6,7
1Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and StatisticS (CRESS), Paris F-75004, France.
The Lancet regional health. Europe
|April 11, 2025
概括
减肥手术 (BS) 后的怀孕显示出较少的孕产妇并发症,但增加了新生儿的风险,包括怀孕年龄小 (SGA) 和早产. 这些风险被营养不良和手术和怀孕之间的间隔缩短所放大.
科学领域:
- 生殖健康 生殖健康
- 腹部外科手术的结果
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 减肥手术 (BS) 后怀孕的发病率增加.
- 对早产和死产等风险的先前研究结果存在矛盾.
- 需要确定BS后的最佳受孕时间.
研究的目的:
- 为了检查怀孕后腹部外科手术的孕妇和新生儿的结果.
- 确定影响这些结果的因素.
- 将结果与手术前怀孕和对照进行比较.
主要方法:
- 法国BS后怀孕 (2013-2022) 的全国性回顾性研究.
- 55941例BS后怀孕与223712例对照进行了比较.
- 在同一女性中,11777次BS后怀孕与11777次BS前怀孕的比较.
主要成果:
- 在BS后的怀孕中,孕期高血压,孕前和孕期糖尿病的风险有所降低.
- 与对照组相比,观察到小于妊娠年龄 (SGA) 和早产的风险增加.
- 营养不良,较短的BS-to-conception间隔 (<12个月) 和胃绕道术的SGA和早产风险更高.
结论:
- 后BS怀孕与更好的母亲结果,但更糟糕的新生儿结果有关.
- 较短的间隔,营养不良和胃绕道术增加了新生儿的风险 (SGA,早产).
- 后BS怀孕需要密切监测营养和产科并发症.
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