针对乳腺癌的瘤微环境的知识映射:从2014年到2023年的文献计量分析
Dongping Jiang1,2, Ping Wen1,2, Senmiao Zhang1,2
1Chongqing University Cancer Hospital, School of Medicine, Chongqing University, Chongqing, China.
Frontiers in immunology
|April 11, 2025
概括
这份对乳腺癌瘤微环境 (TME) 研究的文献分析显示,免疫疗法和转移是重点领域. 癌症免疫疗法是TME研究中的一个关键新兴重点.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 生物信息学是一种生物信息学.
背景情况:
- 乳腺癌是全球女性的主要癌症.
- 瘤微环境 (TME) 对于了解癌症进展,转移和复发至关重要.
- 在TME中确定新的治疗点对于改善患者的治疗结果至关重要.
研究的目的:
- 进行乳腺癌瘤微环境 (TME) 研究的文献分析.
- 确定当前的研究热点,发展趋势和该领域的未来方向.
- 为乳腺癌的TME研究领域提供全面的概述.
主要方法:
- 在科学网数据库中对2014-2023年间的9683篇出版物进行了文献计量分析.
- 使用CiteSpace进行共同引用分析,以评估知识库的演变.
- 使用VOSviewer的关键词,国家,机构和作者同时出现的分析.
- 使用文献计量数据包进行主题演变分析.
主要成果:
- 关键词同时出现的分析确定了五个主要集群:免疫疗法,转移,诊断和预后,代谢调节和治疗方法.
- 免疫疗法和转移是最常提到的关键词.
- 中国是最富有生产力的国家,上海通大学是领先的机构,高是最多产的作家.
结论:
- 与癌症相关的纤维细胞是乳腺癌TME研究中感兴趣的重要领域.
- 在最近的TME研究中,癌症免疫疗法已成为主要焦点.
- 本分析突出了乳腺癌TME研究中的关键趋势和协作网络.
关键词:
圣经计量资料 (Bibliometric bibliometric bibliometric) 是指参考书目中的资料.乳腺癌 乳腺癌 乳腺癌免疫疗法 免疫疗法转移 转移 转移 转移瘤微环境是一个微环境.更多相关视频
11:00Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment
Published on: March 25, 2020
16.9K
09:53Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
Published on: August 16, 2020
6.8K
相关概念视频
The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
