标准化每个结肠癌部分的定义:关于瘤结果临床决策的德尔菲共识
Mehmet Ayhan Kuzu1, Cigdem Benlice1, Amjad Parvaiz2
1Department of General Surgery, School of Medicine, Ankara University, Ankara, Turkey.
Diseases of the colon and rectum
|April 11, 2025
概括
这项研究通过使用Delphi调查建立了关于结肠癌细分部位的国际共识. 专家们同意了"10厘米规则"和解剖学地标,尽管对于重叠的病变仍然存在模糊性.
科学领域:
- 在瘤学瘤学.
- 外科胃肠道外科手术
- 医疗信息学 医疗信息学
背景情况:
- 目前的数据注册缺乏对不同结肠癌位置的标准化分类.
- 这种缺陷阻碍了结肠癌研究中的准确数据分析和比较研究.
研究的目的:
- 为了在定义初级结肠癌细分部位方面达成国际共识.
- 为受癌症影响的结肠的每个部分制定标准化的定义.
主要方法:
- 从2022年12月到2023年6月,与国际专家一起进行了三轮的Delphi在线调查.
- 专家们在一至九的尺度上对17个陈述进行了排名,在最后一轮中,达成共识的得分为7-9和中等/高共识 (超过4为>70%).
- 该研究的重点是精确定位癌症部分,而不是手术治疗的具体情况.
主要成果:
- 共有331名专家参与,所有三轮的完成率都很高 (91%-98%).
- 强烈支持"10厘米规则"和用于定义结肠癌部位的解剖学地标.
- 欧洲和美国的专家达成共识,取消了"直筒形状癌症"一词,与亚洲专家形成鲜明对比;在描述重叠的癌症部分方面达到了64%的共识.
结论:
- 德尔菲调查成功地建立了关于结肠癌细分定义的国际高度共识.
- 支持采用标准化方法,包括"10厘米规则",以改善分类.
- 关于重叠结肠癌病变的精确定义和分类存在持续的模两可.
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