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Updated: May 14, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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核心分子时钟因素通过CSC/EMT途径和脂质滴生物生成来调节骨肉瘤干细胞的生存和行为

Sukanya Bhoumik1, Yool Lee1,2,3,4

  • 1Department of Translational Medicine and Physiology, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.

Cells
|April 11, 2025
PubMed
概括

昼夜时钟调节骨髓瘤中癌症干细胞 (CSC) 功能. 核心时钟基因的破坏会损害CSC的生存,迁移和脂质代谢,这表明其具有治疗潜力.

关键词:
癌症干细胞是一种癌症干细胞.昼夜时钟是生物周期的时间表.表皮 mesenchymal 过渡的转变.脂肪液滴滴滴滴滴滴滴滴滴滴滴滴滴滴滴骨质肉瘤是骨质肉瘤的一种疾病.

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