在患有慢性病的儿童中,睡眠呼吸障碍的发生率
Naresh Kumar1, Roselin Juliet Joice2, Roshni Julia Rajan3
1Department of Paediatric Nephrology, Christian Medical College, Tamil Nadu, Vellore, India.
Pediatric nephrology (Berlin, Germany)
|April 11, 2025
概括
睡眠呼吸障碍 (SDB) 影响了近一半患有慢性病 (CKD) 的儿童,即使在早期阶段. 严重程度随着CKD进展而增加,强调了儿童CKD患者需要SDB查的必要性.
科学领域:
- 儿科脏病学 儿科脏病学
- 睡眠医学 睡眠医学
- 心血管健康 呼吸系统健康
背景情况:
- 睡眠呼吸障碍 (SDB) 是患有慢性病 (CKD) 的儿童常见的并发症.
- 以前的估计表明,SDB影响了多达62%的儿科CKD患者.
- 这项研究使用多睡眠学 (PSG) 调查了CKD第2-5阶段的SDB患病率和严重程度.
研究的目的:
- 确定患有CKD阶段2-5的儿童中SDB的患病率和严重程度.
- 为了比较早期 (2阶段) 和高级 (3-5阶段) CKD之间的SDB指数.
- 评估爱普沃思儿童和青少年睡眠度量 (ESS-CHAD) 在确定该人群中SDB的有用性.
主要方法:
- 在印度南部 (2023年3月至12月) 进行的观测性,横截面研究.
- 纳入36名患有CKD阶段≥2的儿童 (5-18岁),包括透析和移植后患者.
- 使用多睡眠学 (PSG) 和ESS-CHAD进行SDB评估;分析呼吸暂停-呼吸暂停指数 (AHI) 进行阻塞性睡眠暂停 (OSA) 诊断.
主要成果:
- 整体OSA患病率为47%,尽管只有6%的人通过ESS-CHAD报告了症状.
- 在早期CKD (2期) 的儿童中,50%的儿童有OSA.
- 中度至重度的OSA主要观察到患有晚期CKD (3-5阶段) 的儿童.
结论:
- 睡眠呼吸障碍在儿科慢性病的所有阶段都非常普遍.
- SDB的严重程度与CKD的晚期有显著的相关性.
- 在患有CKD的儿童中,无论报告的症状如何,对SDB的常规PSG查至关重要.
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