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Updated: May 14, 2025

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

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使用表面修饰生物材料加速外围神经修复,以有针对性地捕获神经瘤后的质衍生生长因子

Shiu-Jau Chen1,2, Chih-Ming Lin3,4, Chiung-Hui Liu4,5

  • 1Department of Medicine, MacKay Medical College, New Taipei, Taiwan.

PloS one
|April 11, 2025
PubMed
概括

这项研究通过使用syndecan-3 (SDC3) 修饰的小肠子粘膜 (SIS) 来增强神经再生,并提供生长因子. 这种生物材料显著促进了轴突生长和在外围神经受伤后的功能恢复.

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Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord20:14

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord

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相关概念视频

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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