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Updated: May 14, 2025

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
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Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Published on: November 4, 2016

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Vps34编排的脂质信号传递过程调节了效应器调节性T细胞的过渡异质性和功能适应

Erienne G Norton1,2, Nicole M Chapman1, Hao Shi1

  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

PLoS biology
|April 11, 2025
PubMed
概括

第三类PI3K Vps34调节效应器调节性T细胞 (Treg) 的异质性和功能. 失去Vps34会损害Treg发育和生存,导致自身免疫,但减少抗瘤免疫力.

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