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Updated: Jun 16, 2026

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq
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在质母细胞瘤中基因型-免疫类型关系的单细胞剖析

Nishant Soni1, Kavita Rawat2, Zhihong Chen2,3

  • 1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Brain : a journal of neurology
|April 11, 2025
PubMed
概括

这项研究揭示了质母细胞瘤 (GBM) 的特定遗传驱动因素如何影响其瘤微环境 (TME). 了解这些基因型-免疫类型的关系是开发针对性治疗这种侵袭性脑癌的关键.

关键词:
基因工程小鼠模型的基因工程.质母细胞瘤是一种质母细胞瘤.骨髓状细胞多样性的多样性单细胞基因组学 单细胞基因组学瘤异质性的异质性

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