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Updated: May 14, 2025

Oligopeptide Competition Assay for Phosphorylation Site Determination
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埃尔克体激活:两个有序酸化事件的重要性

Clil Regev1, Hyunbum Jang2, Ruth Nussinov3

  • 1Cancer Innovation Laboratory, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

Journal of molecular biology
|April 11, 2025
PubMed
概括

ERK的激活需要双化,化位点的顺序对于激酶稳定性和催化作用至关重要. 这项研究揭示了ERK的全性酸化代码.

关键词:
在ERK2的基础上.激活循环的启动循环.双化位点是双化位点.分子动力学分子动力学通过连续的酸化.

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