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阿米奥达龙毒性的脂质组景观:一种以脂质为中心的体内多组体研究

Nguyen Quang Thu1, Jung-Hwa Oh2, Nguyen Tran Nam Tien1

  • 1Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan 47392, Republic of Korea.

Toxicology and applied pharmacology
|April 11, 2025
PubMed
概括

阿米奥达龙治疗在老鼠中引起显著的脂质组和基因表达变化,揭示了药物诱导的肝损伤背后的潜在机制. 这项研究突出显示了脂质代谢和信号通路的干扰,导致阿米奥达龙的肝毒性.

关键词:
艾米奥达龙是一种阿米奥达龙.肝毒性 肝毒性 肝毒性在活体中,在活体中.利皮多米克 (Lipidomics) 是一种消化剂.脂肪毒性 脂肪毒性文字转录学 (Transcriptomics) 是一个学科.

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