设计一个可互操作的解决方案,以支持药物基因组指导的处方在初级保健:一个实施者报告
Videha Sharma1, John McDermott2,3, Jessica Keen3
1Centre for Health Informatics, Division of Informatics, Imaging and Data Science, The University of Manchester, Manchester, UK videha.sharma@manchester.ac.uk.
一个新的可互操作的解决方案使得在英格兰的初级保健中可以使用药物基因学指导的处方. 这种基于标准的,不依赖于供应商的方法将药物基因组数据和指导整合到护理地点的电子健康记录 (EHR) 中.
科学领域:
- 医疗信息学 医疗信息学
- 临床药理学 临床药理学
- 基因组学就是基因组学.
背景情况:
- 药物基因组学通过基于基因构成预测药物反应来提供个性化医疗.
- 在常规临床实践中,特别是初级保健中,实施药物基因组指导的处方提出了重大技术和工作流程挑战.
研究的目的:
- 描述在英格兰国家卫生服务 (NHS) 内的药物基因组指导处方的互操作解决方案的实施.
- 开发一个系统,将药物基因组数据和临床指导整合到初级保健电子健康记录 (EHR) 中.
主要方法:
- 采用了一种代软件开发方法,包括临床工作流程映射,系统架构设计,开发和试点测试.
- 一个商业健康数据管理平台被配置为存储结构化药物基因组学结果.
- 为服务部署开发了一个开放的应用程序编程接口 (API),使数据交换成为可能.
主要成果:
- 该解决方案以结构化格式存储药物基因组学结果和指导知识库.
- 它通过开放的API作为服务部署,允许第三方系统使用患者和药物标识符查询药物基因组数据.
- 该系统与现有的临床决策支持工具集成,为处方者在其电子健康记录中提供上下文信息.
结论:
- 一个可互操作的,无关供应商的,基于标准的解决方案对于在各种护理环境中实施药物基因组指导的处方至关重要.
- 通过API将数据与应用程序分开,便于与各种电子健康记录系统集成,最大限度地提高了处方时的药物基因组信息的实用性.
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