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Alvaro Banderas1,2, Maud Hofmann3, Céline Cordier3

  • 1Institut Curie, Université PSL, Sorbonne Université, CNRS UMR168, Physics of Cells and Cancer, Paris, France alvaro.banderas@leibniz-inm.de.

Life science alliance
|April 11, 2025
PubMed
概括

研究人员设计了光控制的酵母激素信号,以精确地塑造细胞通信. 这种光遗传工具可以对细胞生长,融合和基因表达进行空间控制,从而推进生物工程和细胞群的定量建模.

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Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
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