相关实验视频
神经学的表观遗传修饰的新兴趋势和热点:一个图书法分析分析
Shu-Ying Xu1, Siyao Zhang2, Chun-Li Zeng3
1Department of Acupuncture-Moxibustion, Tuina and Rehabilitation, Kunshan Hospital of Traditional Chinese Medicine, Kunshan Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, SuZhou, China.
Molecular neurobiology
|April 11, 2025
概括
神经学的表观遗传学研究正在迅速扩大,重点是阿尔茨海默氏症和精神分裂症等脑疾病中的DNA甲基化和基因表达. 这一趋势表明未来有希望的治疗干预措施.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
- 生物化学 生物化学
背景情况:
- 表观遗传修饰在神经功能和疾病中至关重要.
- 神经表观遗传学领域已经出现了实质性的增长.
- 了解这些修改是开发新治疗方法的关键.
研究的目的:
- 分析神经学中表观遗传修饰的演变和未来趋势.
- 确定该领域的关键研究领域,机构和作者.
- 绘制神经表观遗传学的协作网络和核心主题的地图.
主要方法:
- 在2004年至2024年期间,对12964篇出版物的图书统计分析.
- 使用了R的文献计量软件包,VOSviewer和Scimagp Graphica. 这两种软件.
- 关键词分析和手动审查研究主题和疾病.
主要成果:
- 在表观遗传神经学研究的显著增长,美国作为主要贡献者.
- 自然是顶级的期刊;J. 米尔和E.J. 在一起. 尼斯特勒是被大量引用的作家.
- 关键的研究术语包括"表达"",DNA甲基化"",大脑"",基因表达"",基因".
- 阿尔茨海默病,癌症和精神分裂症是主要的相关疾病.
- 专注于DNA甲基化,氧化应激,突触可塑性和BDNF基因.
结论:
- 神经学领域的表观遗传学研究正在加剧,未来探索的轨迹已经明确.
- 这些发现突显了新的治疗方法和干预措施的潜力.
- 预计将在探索表观遗传机制和临床相关性方面继续扩大和专业化.
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