IgM

Alexander Pöhler1, Uwe Wessels2, Roland F Staack2

  • 1Roche Pharma Research & Early Development (pRED), Pharmaceutical Sciences, Bioanalysis & Biomarkers, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, 82377, Penzberg, Germany. alexander.poehler@roche.com.

The AAPS journal
|April 11, 2025
PubMed
概括

一个新的蛋白酶选择性地切割IgM,改善免疫测试. 这种方法消除了类风湿因子干扰,并简化了IgM同型定型,在基因治疗研究中揭示了以前低估的免疫反应.