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一个多站点,多模式的移动头部资源,用于大脑MRI协调

Shaun Warrington¹, Andrea Torchi¹, Olivier Mougin²

¹Sir Peter Mansfield Imaging Centre, Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.

Scientific data

|April 11, 2025

概括

本研究介绍了ON-Harmony资源,这是一个用于磁共振成像 (MRI) 协调的综合数据集. 它解决了扫描仪的变异性,以提高脑成像研究的可复制性和可量化性.

科学领域:

神经成像是一种神经成像.
医学物理医学物理
生物医学工程生物医学工程

背景情况:

磁共振成像 (MRI) 对于研究活体大脑至关重要.
像扫描仪变异这样的非生物因素限制了MRI的可复制性和可量化性.
标准化是必要的,以克服这些局限性在多站点神经成像研究.

研究的目的:

介绍牛津-诺丁汉协调 (ON-Harmony) 资源,这是MRI协调的综合数据集.
为绘制MRI数据中的生物,扫描器间和扫描器内部变异性提供资源.
为了促进MRI协调方法的评估.

主要方法:

利用一个旅行头的范式与20名健康的志愿者.
在五个地点扫描了来自三家供应商 (GE,飞利浦,西门子) 的六台3T核磁共振扫描仪的参与者.
采集了五种成像模式 (T1w,T2w,dMRI,rfMRI,SWI) 的数据,使用了与英国生物库一致的协议,其中包括一些参与者的扫描器内重复.

主要成果:

产生了165个多模式扫描会话.
收集的数据使得可以绘制数百个MRI衍生措施的各种变异源的映射.
在ON-Harmony资源是公开可用于研究使用.

结论:

ON-Harmony资源是神经成像社区的宝贵资产.
它支持MRI协调技术的开发和验证.
这种资源将促进MRI研究的可复制性和量化性.

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