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Updated: May 14, 2025

A Nonsequencing Approach for the Rapid Detection of RNA Editing
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A Nonsequencing Approach for the Rapid Detection of RNA Editing

Published on: April 21, 2022

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通过Cas13b-ADAR2复合体进行RNA引导RNA编辑的结构洞察

Junichiro Ishikawa1, Kazuki Kato2, Soumya Kannan3,4,5,6

  • 1Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.

Nature structural & molecular biology
|April 11, 2025
PubMed
概括

研究人员揭示了Cas13-RNA复合体的结构,推进了RNA编辑技术. 这项工作揭示了RNA分裂和编辑的机制,为改进基因治疗中的CRISPR-Cas13应用铺平了道路.

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