预测术后静脉血栓栓塞的风险在鼻膜整形患者:一个队列研究
Jie Chen1, Jianfei Zhang1, Xia Xiao1
1Department of Burns and Plastic Surgery, Hengyang Medical School, The Second Affiliated Hospital, University of South China, No. 35 Jiefang Avenue, Zhengxiang District, Hengyang, 421001, China.
在鼻整形手术中确定静脉血栓塞栓症 (VTE) 风险因素至关重要. 炎症性肠病,心肌梗塞,先前的静脉动脉瘤,肋骨移植和先前的鼻腔手术独立地增加了鼻整形后的静脉动脉瘤风险.
科学领域:
- 整形外科 整形外科 整形外科
- 血管外科 血管外科
- 医疗信息学 医疗信息学
背景情况:
- 静脉血栓塞栓症 (VTE) 是鼻整形术后的一种罕见但严重的并发症,发生率明显低于整形外科手术.
- 了解鼻整形中VTE的特定风险因素对于患者安全和临床实践至关重要.
- 这项研究调查了风险因素,以改善VTE预防策略在鼻整形患者.
研究的目的:
- 确定和分析手术后静脉血栓塞栓症 (VTE) 的独立风险因素,用于接受鼻整形手术的患者.
- 开发和验证VTE风险预测模型,用于鼻整形患者.
- 为临床医生提供一个工具,以更好地评估风险和患者管理.
主要方法:
- 对1100名鼻整形患者的回顾性分析 (2016年1月 - 2022年1月).
- 分为非VTE (1012例) 和VTE (88例) 组,根据一个月内术后发生的VTE.
- 多变量逻辑回归和名ogram模型构建与启动用于验证.
主要成果:
- 统一分析显示,在VTE组中,炎症性肠病 (IBD),心肌梗塞,先前的VTE,PICC/中央线使用,肋骨移植使用和鼻腔手术史的比例更高.
- 多变量分析确定IBD,心肌梗塞,以前的VTE,肋骨移植和鼻腔手术史作为VTE的独立风险因素 (P <0.05).
- 预测性名图表显示了良好的校准和准确性 (AUC = 0.845).
结论:
- 炎症性肠病,心肌梗塞,先前的静脉动脉瘤,肋骨移植和鼻腔手术史是鼻膜整形术后静脉动脉瘤的重要独立风险因素.
- 开发的预测模型准确地评估了鼻整形患者的静脉瘤风险.
- 这些发现为临床决策和鼻美术风险分层提供了宝贵的指导.
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