在评估疑似感染性内分心炎 (TEASE) 患者中的胸外心声学:一项探索性研究
Nello Cambise1, Saverio Tremamunno2, Angelo Giuseppe Marino1
1Dipartimento di Scienze Cardiovascolari e del Torace, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
对于疑似感染性内心炎 (IE) 和阴性胸前心声图 (TTE) 的患者,可以确定特定的子组. 这些发现表明,在某些低风险患者中,可以安全地避免或延迟经食管回声心电图 (TEE).
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 诊断成像 诊断成像 诊断成像
背景情况:
- 越来越多地建议通过食道心声学 (TEE) 诊断感染性内心炎 (IE).
- 胸前回声心电图 (TTE) 是主要的诊断工具,但其负面结果需要进一步调查.
- 识别可能不需要TEE的患者可以优化资源配置和患者管理.
研究的目的:
- 确定是否可以识别出可以避免或延迟TEE的阴性TTE患者子组.
- 分析最初TTE结果为负的患者感染性内心炎的预测因子.
- 完善疑似IE的诊断策略,提高效率和患者护理.
主要方法:
- 对637名连续接受TEE的患者进行了回顾性研究,因为他们怀疑IE.
- 分析的重点是375名带有阴性TTE结果的患者.
- 关键变量包括:血液培养结果,血栓塞的证据,心脏膜疾病,膜假肢,心脏器械和血小板计数.
主要成果:
- 在56名患者中诊断出感染性内心炎 (IE).
- 对IE的独立预测因素包括:阳性血培养,血栓塞的证据,生物假体心脏门和低血小板计数 (<150,000/mL).
- 没有这些预测因素的患者 (n=81) 的IE诊断率非常低 (1/81),并且没有住院死亡率.
结论:
- 可以确定疑似IE和阴性TTE患者的子组.
- 这些低风险子组可能是安全避免或延迟TEE的候选人.
- 这种分层可以帮助优化在IE评估中使用先进的诊断成像.
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