皮肤穿透左心室尾关闭:支持证据,局限性和未来方向
Giuseppe Imperatore1, Stijn Lochy2, Mohamed Ben Yedder3
1Health Science Interdisciplinary Centre, Sant'Anna School of Advanced Studies, 56127 Pisa, Italy.
Journal of clinical medicine
|April 12, 2025
概括
穿皮左心室尾阻塞 (LAAO) 为无法使用抗凝剂的心房患者提供了一种中风预防替代方案. 这次审查评估了LAAOO的LAAO.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械技术 医疗器械技术
背景情况:
- 心房动 (AF) 具有显著的中风风险,通常用抗凝药进行治疗.
- 对一些AF患者来说,长期抗凝药是禁忌的.
- 穿皮左心室尾阻塞 (LAAO) 已成为另一种预防中风的策略.
研究的目的:
- 综合审查LAAO程序的有效性和安全性.
- 巩固来自临床试验和现实研究的现有证据.
- 确定当前LAAO研究的局限性,并概述未来的方向.
主要方法:
- 对LAAO发表的临床试验和现实世界的数据进行系统审查.
- 对程序成功率,安全结果和长期疗效的分析.
- 评估患者选择标准,程序技术和后续协议.
主要成果:
- 在选择的AF患者中,LAAO在预防中风方面表现出有希望的疗效.
- 安全性概况通常是有利的,并确定了特定的程序风险.
- 在患者选择,技术和随访方面存在变化,影响结果的解释.
结论:
- 对于患有抗凝血药物的禁忌的患者来说,LAAO是一种可行的中风预防选择.
- 需要进一步的研究来规范方案和优化患者选择.
- 解决目前的知识差距将增强LAAO的治疗潜力.
相关概念视频
Imbalances in Cardiac Output
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiac Catheterization II: Right Heart Catheterization
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
Cardiac Catheterization III: Left Heart Catheterization
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Mitral Regurgitation I: Introduction
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...


