左边与左边的对比 在COVID-19患者中右捆分支块:不同的临床表现和预后影响
Elena Ciurariu1, Mara Amalia Balteanu2, Marius Georgescu1,3
1Department of Functional Sciences, Physiology Discipline, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timişoara, Romania.
患有左捆分支阻塞 (LBBB) 的COVID-19患者的临床情况比患有右捆分支阻塞 (RBBB) 的患者更为严重. 心脏和炎症标志物的这种区别表明捆绑分支区块类型影响COVID-19的进展和风险分层.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 内部医学 内部医学
背景情况:
- COVID-19与系统性影响有关,包括心血管并发症.
- COVID-19和心脏导电异常,如捆绑分支阻塞 (BBB) 之间的相互作用尚未得到充分理解.
- 比较COVID-19患者的临床概况,先前存在的左捆分支区块 (LBBB) 与右捆分支区块 (RBBB) 是至关重要的.
研究的目的:
- 为了比较LBBB和RBBB的COVID-19患者在入院时的临床特征.
- 为了确定区分LBBB和RBBB的COVID-19患者的预测因子.
- 探索BBB型对疾病呈现和COVID-19潜在风险分层的影响.
主要方法:
- 研究了一组100名COVID-19患者的前身BBB (50 LBBB, 50 RBBB) 的队列.
- 评估了主要的心脏代谢,脏,血液和炎症标志物.
- 后勤回归和斯皮尔曼的相关性被用于数据分析.
主要成果:
- 与RBBB患者相比,LBBB患者的系统血压较低,但左心脏大小,左心室直径和心室间隔膜厚度较大.
- 血液学和炎症标志物的显著差异被观察到,LBBB患者显示出更高的红细胞分布宽度,淋巴细胞数量,中性粒细胞数量和C反应蛋白.
- 绝对淋巴细胞数量,C反应蛋白和左心室直径是区分LBBB和RBBB的关键预测因素.
结论:
- 患有LBBB和RBBB的COVID-19患者在入院时呈现出不同的临床特征.
- 在LBBB组显示出更不利的基线概况,特别是关于心脏和炎症标志物.
- 以前存在的BBB类型可能会影响COVID-19疾病的进展,有助于风险分层.
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