在重大腹部和胸部外科手术中注射甲状腺吗啡:观察性研究
Silvia González-Santos1, Antía Osorio-López1, Borja Mugabure-Bujedo1
1Department of Anesthesiology, Postoperative Care and Pain Management, Donostia University Hospital, 20014 San Sebastián, Spain.
Healthcare (Basel, Switzerland)
|April 12, 2025
概括
内吗啡是一种安全有效的区域技术,用于管理大手术后的急性术后疼痛. 这项研究没有发现呼吸系统抑郁症,而阿特莱克塔斯症的发病率较低,需要呼吸系统支持.
科学领域:
- 麻醉学和疼痛管理
- 术后恢复 术后恢复
- 区域麻醉技术 区域麻醉技术
背景情况:
- 有效的术后疼痛管理对于患者的康复至关重要,减少住院时间和医疗保健费用.
- 内吗啡提供长时间的止痛作用,使其适合于各种重大手术手术.
- 在重大腹部和胸部外科手术中,评估内吗啡的安全性和有效性至关重要.
研究的目的:
- 评估内吗啡在重大手术中的急性术后疼痛控制方面的安全性.
- 为了确定呼吸系统抑郁的发病率,脱氧,以及需要呼吸系统的支持.
- 评估二次结果,包括救援止痛药的使用,术后恶心和吐 (PONV),以及晚期并发症.
主要方法:
- 在重大腹部或胸部手术 (2018-2021) 后,484名接受内吗啡的患者进行了回顾性观察性研究.
- 主要安全终点包括呼吸抑郁症,阿特莱克塔斯症和呼吸支需求.
- 二级终点包括救援IV吗啡消耗,PONV,肺炎,再入院,再手术,住院和死亡率.
主要成果:
- 没有报告呼吸系统抑郁的情况.
- 在2.07%的患者中发生了Atelectasis;1.86%需要呼吸辅助 (NIMV/HFOT).
- 51%需要救援IV吗啡;PONV发病率为30.37%. 胸部和整体外科组的救援吗啡需求比泌尿外科更高.
结论:
- 内吗啡是一种安全的技术,用于在重大腹部和胸部手术中管理急性术后疼痛.
- 它很好地集成到多式模式疼痛管理策略中.
- 虽然通常是安全的,但需要仔细考虑患者因素和手术类型,以获得最佳的结果.
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