与慢性细菌性前列腺炎患者的微生物学发现有关的性功能评估
Vittorio Magri1, Gianpaolo Perletti2, Konstantinos Stamatiou3
1Urology Clinic, ASST Fatebenefratelli Sacco Hospitals, 20026 Milan, Italy.
Diagnostics (Basel, Switzerland)
|April 12, 2025
概括
慢性细菌性前列腺炎 (CBP) 显著影响性健康,格拉姆阴性感染增加勃起功能障碍和高潮问题的风险. 了解感染类型有助于患者管理.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 微生物学 微生物学
- 性医学性医学性医学性医学
背景情况:
- 慢性细菌性前列腺炎 (CBP) 经常与男性患者的性功能障碍有关.
- 感染位置和病因因子对CBP性健康结果的特定影响需要进一步调查.
研究的目的:
- 评估感染位置和病因如何影响诊断为CBP的患者的性功能障碍.
- 为了将临床发现和病因因素与经过验证的性功能问卷相关联.
主要方法:
- 评估了614名男性患者的队列,其中有微生物学确认的CBP.
- 使用标准化问卷来评估前列腺炎症状 (NIH-CPSI),排泄问题 (IPSS) 和性功能 (IIEF-15,PEDT).
- 对表达前列腺分泌物 (EPS) 和前列腺按摩后尿液 (VB3) 的微生物学分析确定了感染病因.
主要成果:
- 观察到性功能障碍的高患病率:勃起功能障碍 (49.8%),早泄 (40.7%) 和至少一个性障碍 (86.3%).
- 与非典型病原体相比,格兰阴性感染与中度至重度勃起功能障碍 (OR 3.31) 和高潮功能障碍 (OR 3.2) 的更高几率有关.
- 格拉姆阳性感染显示出血清率的增加 (OR 2.2984) 并与高潮功能障碍相关 (OR 3.78).
- 与格拉姆阳性感染相比,与格拉姆阴性感染相比,前列腺结的频率较低 (OR 0.471).
结论:
- 在CBP中,阴性细菌感染与增加的性病率有显著的关联.
- 将性领域纳入UPOINT等分类系统可以改善与症状严重程度 (NIH-CPSI) 的相关性.
- 综合性功能障碍评估对于有效的患者表型和慢性前列腺炎的管理至关重要.
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