超加工食品及其对骨健康和关节疾病的影响:一个全面的综述
Jacopo Ciaffi1,2, Luana Mancarella1, Claudio Ripamonti1
1Medicine & Rheumatology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Nutrients
|April 12, 2025
概括
超加工食品 (UPF) 对骨健康产生负面影响,增加骨质疏松症和骨关节炎等关节疾病的风险. 对于骨和关节健康,建议采用更健康的饮食模式.
科学领域:
- 营养科学 营养科学
- 类风湿病学 类风湿病学
- 骨健康研究 骨健康研究
背景情况:
- 超加工食品 (UPF) 在全球范围内越来越普遍.
- 越来越多的证据表明,UPF可能会对慢性疾病产生负面影响.
- UPF对骨健康和关节疾病的具体影响需要全面审查.
研究的目的:
- 对超加工食品消费与骨健康之间的关联进行范围审查.
- 检查UPF与各种关节疾病,包括骨关节炎和炎症性关节炎之间的关系.
- 综合目前关于UPFs对骨矿物质密度,骨质疏松症和关节炎影响的证据.
主要方法:
- 开发了一个使用关键词的搜索策略,比如"超加工食品"和"快餐".
- 包括与骨健康损害和关节疾病 (骨关节炎,类风湿性关节炎,痛风,脊髓关节炎) 相关的术语.
- 综合了来自19项纳入研究的结论.
主要成果:
- 临床前研究表明,UPFs对骨结构和强度产生不利影响.
- 最近的研究将较高的UPF摄入量与较低的骨矿物密度和骨质疏松症风险增加联系起来,特别是在绝经后的妇女中.
- UPF消费与膝关节关节炎和炎症性关节炎 (RA,痛风) 的风险增加有关,但不是关节炎或脊椎关节炎.
结论:
- 超加工食品在骨健康和关节疾病中起着有害的作用.
- 有证据支持建议更健康的饮食模式,以减轻与UPF消费相关的风险.
- 需要进一步的研究,以充分阐明将UPF与肌肉骨疾病联系在一起的机制.
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