营养素和天然物质用于糖尿病视网膜病变的低血糖影响和管理
Francesco Cappellani1, Roberta Foti2, Giulia Malaguarnera3
1Department of Ophthalmology, University of Catania, 95123 Catania, Italy.
Nutrients
|April 12, 2025
概括
营养素和天然化合物在控制血糖和糖尿病视网膜病变方面表现有前途. 需要进一步的临床研究来证实它们在综合治疗中的有效性和安全性.
科学领域:
- 内分泌学和新陈代谢学
- 眼科医生 眼科 眼科
- 营养科学 营养科学
背景情况:
- 糖尿病视网膜病变 (DR) 是导致视力障碍和失明的主要原因,源于糖尿病 (DM).
- 高血糖的有效管理对于预防和减轻DR进展至关重要.
- 传统的治疗可以补充营养和具有低血糖特性的天然化合物.
研究的目的:
- 审查和综合有关营养素和具有低血糖作用的天然化合物的现有知识.
- 探索它们在预防和管理糖尿病视网膜病变中的作用机制.
- 巩固关于它们在DR补充治疗中的潜在作用的信息.
主要方法:
- 对PubMed,Scopus和Web of Science的研究进行了全面的文献评论.
- 专注于自然物质,营养素或食补充剂影响血糖和DR相关途径的精选论文.
- 基于机制,疗效和安全性概况的综合发现.
主要成果:
- 鉴定了可以改善胰岛素敏感性和降低氧化应激的营养素 (欧米茄-3脂肪酸,维生素D) 和多 (黄素,白醇).
- 突出自然物质 (柏柏林,氨酸,黄类) 影响炎症,AGE和血管生成与DR相关.
- 当将天然化合物与常规抗糖尿病药物相结合时,观察到潜在的协同效益,以提高血糖控制和视网膜保护.
结论:
- 营养素和天然化合物为血糖调节和糖尿病视网膜病变治疗提供了有希望的辅助策略.
- 需要进一步进行广泛的临床研究来验证疗效,确定最佳剂量,并确保长期的安全性.
- 将这些天然药物纳入临床实践可以提高糖尿病及其眼部并发症的综合管理.
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