微注塑成型PLA/PCL/生物活性玻璃复合材料的结构和性能演变
Meiqiong Chen1, Yinghong Chen1, Haihao He1
1National Key Laboratory of Advanced Polymer Materials, Polymer Research Institute of Sichuan University, Chengdu 610065, China.
Polymers
|April 12, 2025
概括
微注射成型制造了具有增强机械性能和体外生物活性的聚乳酸 (PLA) /聚烯酸 (PCL) /生物活性玻璃 (BG) 复合材料. 这一过程显示出可生物降解生物医学材料的工业应用的前景.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物工程 聚合物工程
- 生物医学工程 生物医学工程
背景情况:
- 可生物降解的聚合物,如聚乳酸 (PLA) 和聚烯酸 (PCL),对于生物医学应用至关重要.
- 纳入生物活性玻璃 (BG) 可以提高聚合物复合材料的生物性能.
- 开发高效的制造技术对于这些材料的工业化至关重要.
研究的目的:
- 使用微注塑成型制备聚乳酸 (PLA) /聚烯酸 (PCL) /生物活性玻璃 (BG) 复合材料.
- 研究不同BG含量对复合材料微观结构,机械性能和体外生物活性的影响.
- 评估微注塑成型在生产先进可生物降解生物医学材料方面的潜力.
主要方法:
- 微注塑被用来制造具有不同BG度的PLA/PCL/BG复合材料.
- 描述涉及扫描电子显微镜 (SEM),X射线衍射 (XRD),富里埃变换红外光谱 (FT-IR),水接触角 (WCA) 测试和机械测试.
- 进行了体外生物评估,包括对模拟体液 (SBF) 中的酸 (HA) 形成的评估.
主要成果:
- 微注塑诱导在现场PCL纤维的形成和BG颗粒在PLA/PCL矩阵中的均分散.
- 随着BG含量,PLA/PCL/BG复合材料的Young模量显著增加,达到2122.9 MPa,重量为10%的BG (比未填充的PLA/PCL高1.47倍).
- BG填充剂在SBF中的样本表面促进了转化为酸 (HA),增强了体外生物活性.
结论:
- 微注塑成型是生产具有改善机械性能和生物活性的PLA/PCL/BG复合材料的有效技术.
- 微注塑成型产生的扩散和结构变化有助于提高材料性能.
- 这些可生物降解的复合材料显示出生物医学领域的工业应用的巨大潜力.
相关概念视频
Polymer Classification: Architecture
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
Polymer Classification: Crystallinity
Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
Molecular Weight of Step-Growth Polymers
Step growth polymerization involves bi or multifunctional monomers. Bifunctional monomers react to form linear step growth polymers, whereas multifunctional monomers react to form non-linear or branched polymers.
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
Types of Step-Growth Polymers: Polyesters
The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
Classification and Mechanical Properties of Synthetic Polymers
Synthetic polymers are classified as elastomers, fibers, or plastics based on their crystallinity. Crystallinity, the degree of long-range order in the solid state, influences the mechanical properties (stretching or contracting) of elastomers. Elastomers are flexible polymers that can expand or contract easily upon the application of an external force. They have numerous crosslinks that pull them back into their original shape when stress is removed. Silicones, for instance, are highly elastic...
Bioplastics
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...


