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相关概念视频

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Protons bonded to heteroatoms such as nitrogen and oxygen exhibit a range of chemical shift values. This is due to the varying degree of hydrogen bonding between the proton and the heteroatom in other molecules. The extent of hydrogen bonding affects the electron density around the proton, thereby giving different chemical shift values for the protons in the proton NMR spectrum.
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相关实验视频

Updated: Jun 19, 2026

Infant Auditory Processing and Event-related Brain Oscillations
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用ABR进行听觉时间解决的客观措施.

Esma Akis1, Steven L Bell1, David M Simpson1

  • 1Institute of Sound and Vibration Research, University of Southampton, Southampton, UK.

International journal of audiology
|April 12, 2025
PubMed
概括

客观的听觉脑干响应 (ABR) 方法对在小组中测量时间分辨率有希望. 然而,由于变异性,个体测量仍然具有挑战性,随着时间划分噪声与点击 (TNNC) 范式显示出更好的重复性.

科学领域:

  • 听觉神经科学 听觉神经科学
  • 神经生理学 神经生理学
  • 信号处理 信号处理

背景情况:

  • 准确测量听觉时间分辨率对于理解听觉处理至关重要.
  • 客观的电生理学方法,如听觉脑干反应 (ABR),是为了补充行为评估.
  • 现有的ABR范式需要验证以可靠地确定时间分辨率值.

研究的目的:

  • 开发和验证使用ABR测量时间分辨率值的客观方法.
  • 为了比较"两次点击 (2C) "和"点击 (TNNC) 的时间划分噪声"ABR范式的有效性.
  • 评估这些客观ABR范式的测试-重新测试可靠性.

主要方法:

  • 评估了"两次点击 (2C) "和"点击时的时间划分噪声 (TNNC) "的ABR范式.
  • 采用统计方法进行客观的ABR检测.
  • 使用科恩的卡帕评估测试-重新测试可靠性.
  • 将ABR结果与噪声间隙和心理测量TNNC测试中的行为值进行比较.

主要成果:

  • 目标时间分辨率值平均为4.04毫秒 (2C) 和3.21毫秒 (TNNC).
  • 组级ABR显示振幅降低和接近值的检测;个体振幅有所不同.
关键词:
时间解决方案 时间解决方案听觉脑干反应的响应前方和后方的掩盖.配对的点击声是一对一对.这是一次超值的听证会.只有两次点击即可.

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  • 行为值为1.49ms (噪声间隙) 和2.22ms (心理测量TNNC).
  • TNNC表现出中度的测试重复测试可重复性,而2C表现出轻微的,不显著的可重复性.

    • 结论:

    • 目标ABR方法显示了对集团层面的时间解决评估的潜力.
    • 高个体变异性目前限制了这些客观措施的临床应用.
    • 与2C范式相比,TNNC范式表现出优越的ABR重复性.