在新生儿和婴儿中使用逆行选择性下体 perfusion 重建大动脉的急性功能衰竭的术后发生率
Thomas Simon Zajonz1, Fabian Edinger1, Ronja Beran2
1Pediatric Cardiac Anesthesiology Service, Pediatric Heart Centre, Department of Aaesthesiology Intensive Care Medicine, Pain Therapy, University Hospital Giessen and Marburg GmbH, Campus Giessen, Giessen, Germany.
Journal of cardiothoracic and vascular anesthesia
|April 12, 2025
概括
在儿科大动脉门重建期间,逆行选择性下体输液 (SLP) 显著降低了急性损伤 (AKI) 发生率和尿液输出量增加. 这种技术在新生儿和婴儿中没有显示出血管并发症.
科学领域:
- 心血管外科心血管外科
- 儿童心脏病学 儿童心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 儿科大动脉门重建是复杂的程序,存在损伤的风险.
- 选择性下体输液 (SLP) 是一种在此类手术中用于改善器官输液的技术.
- 逆行SLP对新生儿和婴儿的结局和血管并发症的影响需要进一步调查.
研究的目的:
- 评估逆向选择性下体输液 (SLP) 对尿量和急性损伤 (AKI) 发生率的影响.
- 评估与SLP表面大腿动脉管相关的血管并发症的发生率.
主要方法:
- 从2015年1月到2023年12月,对104名新生儿和婴儿进行了大动脉门重建的回顾性研究.
- 通过大腿动脉导管接受逆行式SLP的45名患者与对照组进行了比较.
- 使用KDIGO标准和尿液输出分析术后的AKI,并对血管并发症进行随访.
主要成果:
- 在SLP组中,立即和手术后6小时内AKI发病率显著降低 (p = 0.001).
- 接受SLP治疗的患者在术后尿量增加,直到第3天 (p ≤0.045).
- 在SLP组中没有观察到血管并发症,直到医院出院.
结论:
- 逆行SLP是一种安全有效的方法,用于减少儿童大动脉门重建中的AKI发病率.
- SLP与手术后尿量改善有关,而不会增加血管并发症.
- 需要进一步的研究来探索逆行性SLP.的长期脏影响.
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