饮食炎症指数与心血管--代谢综合征风险之间的关联:一个横截面研究
Chuanwei Zhao1, Mu Lin2, Yane Yang2
1Department of Cardiology, The Second People's Hospital of Baoshan, Baoshan, Yunnan, China. zhaochuanwei946@163.com.
较高的饮食炎症指数 (DII) 评分,表明一种更有利于炎症的饮食,与患心血管--代谢综合征 (CKMS) 的风险增加有关. 在一项针对美国人口的大型研究中,发现这种关联是非线性的.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 饮食性炎症与各种慢性疾病有关.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
- 心血管--代谢综合征 (CKMS) 是一个严重的健康问题.
研究的目的:
- 研究DII与美国人口中CKMS风险之间的关联.
- 要确定DII和CKMS之间的关系是线性的还是非线性的.
主要方法:
- 来自国家健康和营养检查调查 (NHANES) (2001-2020) 的24,071名参与者的横截面数据的分析.
- 慢性病综合症 (CKMS) 是指心脏代谢综合症 (CMS) 和慢性病 (CKD) 的同时发生.
- 用于评估关联和非线性趋势的加权多变量逻辑回归和受限立方线回归 (RCS).
主要成果:
- 较高的DII四分位数与CKMS风险显著增加有关.
- 每增加1个单位的DII与12%更高的CKMS风险相关 (OR:1.12,95%CI: [1.08,1.18]).
- RCS回归证实了DII和CKMS风险之间的显著非线性正相关性.
结论:
- 在DII和美国人口中发展CKMS的风险之间存在非线性正相关性.
- 具有较高炎症潜力的饮食模式可能有助于CKMS的发展.
- 需要进一步的研究来探索因果关系和生物机制.
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