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在先天性心脏手术中为儿科患者提供血液产品:一项回顾性,单中心研究
Perfusion
|April 13, 2025
概括
儿童心脏手术输血在协议更改后显著下降. 红细胞和血小板的使用量下降,年龄和体重影响了输血需求.
科学领域:
- 心脏病学 心脏病学
- 输血医学 输血医学
- 儿科手术 儿科手术
背景情况:
- 在儿童心脏手术中输血具有感染和免疫并发症等风险.
- 在儿童大学医院实施了修订后的血液管理协议.
研究的目的:
- 为了评估血液产品在儿科心脏手术中的利用,实施后协议.
- 分析红细胞,新鲜冷血 (FFP),冷沉积物和血小板使用的趋势.
主要方法:
- 对135名接受心肺旁路手术 (CPB) 的儿科患者进行了回顾性审查.
- 患者分为三个年龄组:<1岁,1-4岁和>4岁.
- 使用Kruskal-Wallis和Spearman的rho测试进行统计分析.
主要成果:
- 从2020年到2023年,红细胞使用量显著下降 (p < .0001).
- 血小板使用量显著下降 (p = .04) 和FFP和冷沉积物使用量显著下降 (p < 0.01).
- 患者体重和红细胞输血需求之间的反相关性 (斯皮尔曼的rho = -0.29,p = .001).
结论:
- 在四年内,人们观察到血液制品使用的显著减少,特别是红细胞和血小板的使用.
- 患者的年龄和体重与红细胞输血需求相反相关.
- 观察到的趋势表明手术技术和血液管理协议的改进,可能提高患者的治疗结果.
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