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作为一种上腺质量呈现的逆皮质内节性施瓦诺瘤的诊断挑战
Badr AbdullGaffar1, Kaldoon Alsel2, Ahmed Thouqeer3
1Pathology section, Dubai hospital, Dubai, United Arab Emirates.
International journal of surgical pathology
|April 13, 2025
概括
主要的内节 schwannoma,在淋巴结的罕见瘤,由于异常特征,呈现诊断挑战. 使用S-100染色进行准确的诊断对于适当的患者管理至关重要.
科学领域:
- 病理学 病理学 病理学
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 主要的内螺旋细胞病变不常见,在诊断上具有挑战性.
- 施瓦诺瘤,通常是外围神经膜瘤,很少发生在淋巴结内.
- 结节内瘤可以模仿其他结节脊柱细胞瘤,需要仔细分化.
研究的目的:
- 报告一个反复发生在关节的淋巴结中的偶发性内 schwannoma 的病例.
- 突出诊断挑战和内节瘤的关键特征.
- 强调在结节状细胞病变的差异诊断中考虑结节内瘤的重要性.
主要方法:
- 对逆皮质淋巴结瘤的组织病理学检查.
- 免疫组织化学染色,包括强烈的S-100阳性和其他状细胞瘤标志物的负染色.
- 临床相关性与偶然发现的上腺质量.
主要成果:
- 一个5.0厘米的结节状脊柱细胞瘤取代了后皮质淋巴结.
- 瘤表现出不同的细胞架构模式,最初模拟其他状细胞病变.
- 通过免疫组织化学 (S-100阳性) 证实了斯瓦诺瘤的诊断.
结论:
- 结节内瘤是一种罕见的实体,应纳入初级结节螺旋细胞瘤的差异诊断.
- 组织病理特征和特定的免疫标志物 (S-100) 对于准确的诊断至关重要.
- 在患者的预后和治疗中,区分内瘤与其他瘤至关重要,因为瘤可以通过切除来治愈.
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