肥胖和骨关节炎患者的身体组成参数与生活质量之间的关系
Jaime González-Gutiérrez1, Juan José López-Gómez1, David Primo-Martín1
1Endocrinology and Nutrition Department, Clinic University Hospital of Valladolid, Valladolid, Spain; Endocrinology and Nutrition Investigation Centre, University of Valladolid, Valladolid, Spain.
Nutrition (Burbank, Los Angeles County, Calif.)
|April 13, 2025
概括
在肥胖和慢性骨关节炎患者中,较高的肌肉质量和相角与更好的生活质量和功能有关. 生物阻抗计可以评估这些影响骨关节炎结果的身体组成因素.
科学领域:
- 类风湿病学 类风湿病学
- 肥胖医学 肥胖医学
- 身体组成分析 身体成分分析
背景情况:
- 慢性骨关节炎和肥胖严重影响患者的生活质量 (QoL) 和功能能力.
- 生物阻抗计 (BIA) 提供了一种评估身体组成的方法,包括肌肉和脂肪质量,这可能会影响疾病的结果.
研究的目的:
- 研究肥胖和慢性骨关节炎患者的BIA和QoL/功能能力测量的身体组成参数之间的关系.
- 为了确定特定的BIA衍生的指标是否与骨关节炎症状严重程度相关.
主要方法:
- 一项描述性的横截面研究包括467名患有肥胖和慢性骨关节炎的患者 (74.9%为女性).
- 收集的数据包括人口统计,BMI,WOMAC评分 (评估疼痛,硬,功能) 和BIA参数 (MMI,FMI,PA,BMI调整后PA,Xc,Rz).
- 根据WOMAC总分数,患者被分为四组.
主要成果:
- 肌肉质量指数 (MMI) 和BMI调整后的相角 (PA) 与WOMAC功能能力得分呈负相关性 (r = -0.16,P <0.05).
- 较低的BMI调整的PA与QOL略有下降有关.
- 虽然并非所有指标都具有统计学意义,但趋势表明男性和女性之间的WOMAC分数存在差异.
结论:
- 通过BIA评估的肌肉质量可能与肥胖和慢性骨关节炎患者的QoL有关.
- 减小BMI调整相角与此患者群体的生活质量下降有关.
- BIA参数提供了对身体组成的见解,这可能会影响肥胖个体患有骨关节炎的体验.
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