双分单双胎盘的特征和临床后果
M J A van de Sande1, E Lopriore2, L Lewi3
1Department of Obstetrics, Division of Fetal Therapy, Leiden University Medical Center, Leiden, the Netherlands.
Placenta
|April 13, 2025
概括
双部分单胎盘很少见,但往往具有血管连接. 这些联系可以导致严重的双胞胎妊娠并发症,如双胞胎对双胞胎输血综合征 (TTTS),双胞胎贫血多细胞血序列 (TAPS) 和选择性胎儿生长限制 (sFGR).
科学领域:
- 周围生理学 周围生理学
- 胎儿医学 胎儿医学
- 产科 产科 产科 产科 产科
背景情况:
- 双胞胎胎胎盘与特定的血管解剖学有关.
- 双分胎盘代表了MC双胎盘结构的罕见变化.
- 了解双部分MC胎盘的血管结构对于识别潜在并发症至关重要.
研究的目的:
- 为了研究双分单 (MC) 双胞胎胎胎盘的血管架构 (血管架构).
- 为了确定双部分MC胎盘的临床后果和相关并发症.
主要方法:
- 一项病例控制研究使用来自两个医疗中心的MC双胞胎胎胎盘进行.
- 胎盘注射了彩色染料来分析血管连接.
- 该研究评估了血管瘤的存在和双胞胎对双胞胎输血综合征 (TTTS) 的发生,双胞胎贫血多细胞血序列 (TAPS) 和选择性胎儿生长限制 (sFGR).
主要成果:
- 双分胎盘发生在2.1%的MC双胞胎胎盘中.
- 与非双分胎盘相比,双分胎盘中血管瘤的频率较低,数量也较少.
- 在怀孕中观察到TTTS (26%),TAPS (13%) 和sFGR (5%) 等并发症,这些并发症在怀孕中观察到双重MC胎盘.
结论:
- 在MC双胞胎怀孕中的双分胎盘,虽然很少见,但经常表现出血管瘤.
- 这些瘤的存在表明潜在的风险发展并发症,如TTTS,TAPS,或sFGR.
- 为了改善受影响双胞胎怀孕的管理,需要进一步关注双重MC胎盘的血管架构.
更多相关视频
09:52Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
26.7K
09:51Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
Published on: March 21, 2018
19.5K
相关概念视频
Pathophysiology of Diabetes
818
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
818
Fetal Circulation
643
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
643
Ovarian Cycle
760
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
760
Teratogenicity
2.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.3K
Bipolar Disorder
38
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
38
